What is OPTIMIZE?
The OPTIMIZE Low Back Pain trial is a national pragmatic trial that seeks to understand the proper sequencing of common and effective treatments for chronic low back pain.
Pragmatic trials take place in typical, real-world healthcare clinics. Treatments used in this trial are provided by physical therapists and behavioral health therapists, which include:
- evidence-based physical therapy,
- cognitive behavioral therapy,
- and mindfulness
OPTIMIZE Low Back Pain is funded by the Patient-Centered Outcomes Research Institute (PCORI), an independent, non-profit organization authorized by Congress in 2010.
Its mission is to fund research that will provide patients, their caregivers, and clinicians with the evidence-based information needed to make better-informed healthcare decisions. PCORI is committed to continually seeking input from a broad range of stakeholders to guide its work.