The Summers Laboratory

The Summers laboratory studies the relationship between impaired fat metabolism and the development of diabetes and cardiovascular disease. His group discovered that a particular derivative of fat, termed ceramide, is one of the more toxic metabolites which accumulates in mammals prone to metabolic disorders. His current research efforts are directed at assessing the therapeutic potential of modulating levels of ceramides in the treatment of diabetes and heart disease and elucidating the molecular networks controlling ceramide production and action.


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